Human Galectin 9/LGALS9 Recombinant Protein (RPES4572)

SKU:
RPES4572
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
€122

Description

ELISA Kit Technical Manual

Recombinant Human Galectin 9/LGALS9 Protein (His Tag)(Active)

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Background:Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM, Integrin ?4?1.
Name:Recombinant Human Galectin 9/LGALS9 Protein (His Tag)(Active)
Size:10µg
Assay Genie SKU:RPES4572
Synonyms:Galectin-9; Gal-9; Ecalectin; Tumor Antigen HOM-HD-21; LGALS9
Species:Human
Expression host:Human Cells
Sequence:Met 1-Thr323
Accession:Q3B8N1-2
Mol Mass:36.9 kDa
AP Mol Mass:49 kDa
Tag:C-6His
Bio Activity:Immobilized Human Galectin 9-His at 10?g/ml(100 ?l/well) can bind Cynomolgus TIM-3-His(Cat: PKSQ050023). The ED50 of Human Galectin 9-His is 1.75 ug/ml .
Purity:> 95 % as determined by reducing SDS-PAGE.
Endotoxin:< 1.0 EU per µg as determined by the LAL method.
Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8? for 2-7 days. Aliquots of reconstituted samples are stable at < -20'C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from a 0.2 um filtered solution of PBS,5% Trehalose,1mM EDTA,pH7.4.
Reconstitution:Please refer to the printed manual for detailed information.
Application:Functional ELISA