Interleukin 11 (IL-11) is a human growth hormone, granulocyte colony-stimulating factor, and other growth factors in the same family. CIL-11 is a thrombopoietic growth factor that promotes hematopoietic stem cell and megakaryocyte progenitor cell proliferation and maturation, resulting in enhanced platelet production. It also promotes the growth of hepatocytes in response to injury to the liver. It activates a signaling pathway that promotes cell proliferation by binding to its receptor, which is made up of IL6ST and either IL11RA1 or IL11RA2. Activation of intracellular protein kinases and the phosphorylation of STAT3 occur as a result of the signaling. Human Interleukin1/IL1 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Human Interleukin1/IL1 Recombinant Protein (RPES1750)
Recombinant Human Interleukin-11 is produced by our Yeast expression system and the target gene encoding Gly23-Leu199 is expressed.
> 95% as determined by reducing SDS-PAGE.
AP Mol Mass:
Lyophilized from a 0.2 µm filtered solution of 20mM PB, 2% Glycine, pH 7.2.
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.