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Human PTH1R Recombinant Protein (RPES1209)

SKU:
RPES1209
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
€129

Description

ELISA Kit Technical Manual

Recombinant Human PTH1R Protein (Gly49, His Tag)

Background:Parathyroid hormone 1 receptor(PTH1R) is a multi-pass membrane protein. The protein is expressed in high levels in bone and kidney and regulates calcium ionhomeostasis through activation of adenylate cyclase and phospholipase C. In bone, it is expressed on the surface of osteoblasts. When the receptor is activated through PTH binding, osteoblasts express RANKL (Receptor Activator of Nuclear Factor kB Ligand), which binds to RANK (Receptor Activator of Nuclear Factor kB) on osteoclasts. This turns on osteoclasts to ultimately increase the resorption rate.
Name:Recombinant Human PTH1R Protein (Gly49, His Tag)
Size:10µg
Assay Genie SKU:RPES1209
Synonyms:Parathyroid hormone/parathyroid hormone-related peptide receptor;PTH/PTHrP type I receptor;PTH/PTHr receptor;Parathyroid hormone 1 receptor;PTH1 receptor;PTH1R
Species:Human
Expression host:Human Cells
Sequence:Tyr23-Met 189
Accession:Q0VGD7
Mol Mass:20.2 kDa
AP Mol Mass:30 kDa
Tag:C-6His
Purity:> 95 % as determined by reducing SDS-PAGE.
Endotoxin:< 1.0 EU per µg as determined by the LAL method.
Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8? for 2-7 days. Aliquots of reconstituted samples are stable at < -20'C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
Reconstitution:Please refer to the printed manual for detailed information.