The RNPS1 Polyclonal Antibody (PACO11882) is a valuable tool for researchers studying RNA binding proteins involved in mRNA splicing and processing. This antibody, raised in rabbits, has high specificity and sensitivity for detecting RNPS1 in human samples, making it suitable for use in various research applications such as Western blotting.RNPS1 plays a crucial role in RNA metabolism, specifically in pre-mRNA splicing and mRNA export from the nucleus to the cytoplasm. Dysregulation of RNPS1 has been linked to various diseases, including cancer and neurological disorders.
By using the RNPS1 Polyclonal Antibody, researchers can gain insights into the function of RNPS1 and its role in disease pathogenesis.With its ability to detect RNPS1 in different cell types and tissues, this antibody is an essential tool for studies aiming to understand the molecular mechanisms underlying RNA processing and identify potential therapeutic targets for diseases associated with RNA metabolism dysfunction.
RNA binding protein S1, serine-rich domain;RNPS1;E5.1;MGC117332 ;
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
