The Semaphorin-3A Monoclonal Antibody from AssayGenie is a valuable tool for researchers studying Semaphorin-3A, a protein involved in cell signaling and axon guidance. This antibody, produced using mouse monoclonal technology, is highly specific for Semaphorin-3A and has been validated for use in a variety of research applications, including immunohistochemistry and ELISA.Semaphorin-3A is known for its role in axon guidance during neuronal development, as well as its involvement in immune regulation and cancer progression. By targeting Semaphorin-3A with this monoclonal antibody, researchers can detect and analyze the protein in various cell types, shedding light on its function in both normal physiology and disease states.
This antibody is an invaluable tool for researchers interested in understanding the complex interplay between Semaphorin-3A and various cellular processes. Its high specificity and sensitivity make it ideal for a wide range of research applications, from basic science investigations to drug development efforts targeting Semaphorin-3A-related pathways. Unlock the potential of Semaphorin-3A research with the Semaphorin-3A Monoclonal Antibody from AssayGenie.
Product Name:
Semaphorin 3A Monoclonal Antibody
SKU:
CAB22204
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 582-771 of human Semaphorin 3A (NP_006071.1).
This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.
Purification Method:
Affinity purification
Gene ID:
10371
Clone Number:
ARC56474
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using Semaphorin 3A antibody (CAB22204) at1:20000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
