The SLC41A3 Antibody (PAC023530) is a high-quality polyclonal antibody designed for research involving SLC41A3, a cell membrane transporter protein involved in the regulation of intracellular magnesium levels. The antibody, produced in rabbits, is highly specific to human samples and has been validated for use in various applications, including Western blot and immunofluorescence.SLC41A3 plays a crucial role in magnesium homeostasis, with dysregulation of this protein linked to various diseases, such as osteoporosis, cardiovascular disorders, and neurological conditions.
By targeting SLC41A3 for research, scientists can gain insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets for intervention.The SLC41A3 Antibody (PAC023530) offers reliable detection and analysis of SLC41A3 protein expression in different cell types, making it a valuable tool for studies in physiology, pharmacology, and medical research. By understanding the functions of SLC41A3, researchers can further our knowledge of magnesium regulation and its implications for human health.
Antibody Name:
SLC41A3 Antibody (PACO23530)
Antibody SKU:
PACO23530
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:50-1:100
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthetic peptide corresponding to a region derived from internal residues of human solute carrier family 41, member 3
Form:
Liquid
Storage Buffer:
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Purification Method:
Antigen Affinity Purified
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using at dilution 1/45.
Immunohistochemical analysis of paraffin-embedded Human brain tissue using at dilution 1/45.
Background:
SLC41A3 (solute carrier family 41 member 3) is a 507 amino acid multi-pass membrane protein that belongs to the SLC41A transporter family that includes SLC41A1 and SLC41A2. Localizing to the cell membrane, SLC41A3 contains ten transmembrane domains and is believed to function as a plasma-membrane cation transporter. Its other two family members, SLC41A1 and SLC41A2, have been characterized to function as magnesium transporters and are essential for maintaining magnesium homeostasis within the cell.
Synonyms:
SLC41A1-L2
UniProt Protein Function:
SLC41A3: Belongs to the SLC41A transporter family. 8 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 3q21.2Cellular Component: integral to membrane; plasma membraneMolecular Function: cation transmembrane transporter activity
