The TEX37 Antibody (PACO20788) is a highly specific and sensitive tool for research involving TEX37, a protein with potential implications in cancer biology. This polyclonal antibody, produced in rabbits, exhibits strong reactivity with human samples and has been validated for use in various applications, including Western blot and immunohistochemistry. By binding to TEX37, the antibody enables researchers to detect and analyze the protein in different cell types, making it an ideal tool for studying the role of TEX37 in cancer development and progression.
TEX37 is a relatively unknown protein that has been suggested to play a role in tumorigenesis and cancer cell proliferation. Research into TEX37 has the potential to uncover novel therapeutic targets for cancer treatment, making the TEX37 Antibody an invaluable resource for researchers in the fields of oncology and cancer biology. By utilizing this antibody, researchers can gain deeper insights into the molecular mechanisms underlying cancer and potentially identify new strategies for combating this complex disease.
Antibody Name:
TEX37 Antibody (PACO20788)
Antibody SKU:
PACO20788
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:30-1:150
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human TEX37
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20788(TEX37 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
The second largest human chromosome, 2 consists of 237 million bases encoding over 1,400 genes and making up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr m syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes.
Synonyms:
testis expressed 37
UniProt Protein Function:
TSC21: Chromosomal Location of Human Ortholog: 2p11.2Cellular Component: nucleus
