The ABHD11 Polyclonal Antibody (PAC02209) is a valuable tool for research involving ABHD11, a protein involved in lipid metabolism and cell signaling pathways. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. It binds to the ABHD11 protein, allowing for detection and analysis in a variety of cell types, making it ideal for studies in lipid metabolism, signal transduction, and cell biology.ABHD11 is known to play a role in lipid metabolism, specifically in the hydrolysis of lipid substrates, and has been implicated in various diseases, including metabolic disorders and cancer.
Understanding the function and regulation of ABHD11 is important for unraveling its role in these diseases and potentially identifying new therapeutic targets. The ABHD11 Polyclonal Antibody is a reliable tool for researchers seeking to investigate the role of ABHD11 in various cellular processes and disease pathways.
Antibody Name:
ABHD11 Antibody (PACO22109)
Antibody SKU:
PACO22109
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human ABHD11.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from HUVEC cells and COLO cells, using ABHD11 antibody.
Background:
This gene encodes a protein containing an alpha/beta hydrolase fold domain. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
ABHD11: ABHD11 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Belongs to the AB hydrolase superfamily. 5 isoforms of the human protein are produced by alternative splicing.Protein type: EC 3.-.-.-; HydrolaseChromosomal Location of Human Ortholog: 7q11.23Molecular Function: hydrolase activity
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein containing an alpha/beta hydrolase fold domain. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. [provided by RefSeq, Mar 2016]
