Description
ABHD2 Antibody (PACO24688)
The ABHD2 Polyclonal Antibody (PAC024688) is a valuable tool for researchers studying ABHD2, a protein involved in lipid metabolism and cell signaling pathways. This rabbit-derived antibody is highly specific to human samples and is validated for use in Western blot applications. By binding to ABHD2, this antibody enables researchers to detect and analyze the protein in various cell types, making it ideal for studies in lipid biology and signal transduction.
ABHD2 is known to play a key role in lipid metabolism, particularly in the hydrolysis of bioactive lipids such as monoacylglycerols. Its involvement in cell signaling pathways suggests a potential link to diseases like obesity, diabetes, and cancer. By studying the function of ABHD2, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets.
| Antibody Name: | ABHD2 Antibody (PACO24688) |
| Antibody SKU: | PACO24688 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant Human Monoacylglycerol lipase ABHD2 protein (31-320AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: ABHD2 antibody at 10µg/ml Lane 1: Mouse heart tissue Lane 2: Rat gonadal tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 49 kDa Observed band size: 49 kDa . |
 | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO24688 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human gastric cancer using PACO24688 at dilution of 1:100. |
| Background: | May play a role in smooth muscle cells migration. |
| Synonyms: | Monoacylglycerol lipase ABHD2 (EC 3.1.1.23) (2-arachidonoylglycerol hydrolase) (Abhydrolase domain-containing protein 2) (Lung alpha/β hydrolase 2) (Protein PHPS1-2), ABHD2, LABH2 |
| UniProt Protein Function: | ABHD2: May play a role in smooth muscle cells migration. Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.Protein type: EC 3.1.1.-; Hydrolase; Membrane protein, integral; Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 15q26.1Molecular Function: acylglycerol lipase activity; hormone binding; steroid hormone receptor activityBiological Process: acylglycerol catabolic process; response to progesterone stimulus; sperm capacitation; steroid hormone mediated signaling |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a protein containing an alpha/beta hydrolase fold, which is a catalytic domain found in a very wide range of enzymes. The function of this protein has not been determined. Alternative splicing of this gene results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P08910 |
| NCBI GenInfo Identifier: | 123504 |
| NCBI Gene ID: | 11057 |
| NCBI Accession: | P08910.1 |
| UniProt Secondary Accession: | P08910,Q53G48, Q53GU0, Q5FVD9, Q8TC79 |
| UniProt Related Accession: | P08910 |
| Molecular Weight: | 48,315 Da |
| NCBI Full Name: | Monoacylglycerol lipase ABHD2 |
| NCBI Synonym Full Names: | abhydrolase domain containing 2 |
| NCBI Official Symbol: | ABHD2Â Â |
| NCBI Official Synonym Symbols: | HS1-2; LABH2; PHPS1-2Â Â |
| NCBI Protein Information: | monoacylglycerol lipase ABHD2 |
| UniProt Protein Name: | Monoacylglycerol lipase ABHD2 |
| UniProt Synonym Protein Names: | 2-arachidonoylglycerol hydrolase |
| Protein Family: | Monoacylglycerol lipase |
| UniProt Gene Name: | ABHD2Â Â |
| UniProt Entry Name: | ABHD2_HUMAN |
