The ACAD10 Polyclonal Antibody (PACO05401) is a valuable tool for researchers studying ACAD10, a key enzyme involved in fatty acid metabolism. This antibody, produced in rabbits, is highly specific and reacts with human samples, making it suitable for various applications including Western blot and immunofluorescence.ACAD10, also known as acyl-CoA dehydrogenase family member 10, plays a crucial role in the oxidation of fatty acids and energy production in the mitochondria. Dysregulation of ACAD10 has been linked to metabolic disorders and mitochondrial diseases, making it an important target for research in the fields of metabolism and biochemistry.
By using the ACAD10 Polyclonal Antibody, researchers can accurately detect and analyze ACAD10 protein levels in different cell types and tissues, providing insights into its function and potential implications in various diseases. This antibody is a valuable tool for studies aiming to elucidate the role of ACAD10 in metabolic pathways and develop targeted therapies for related disorders.
Antibody Name:
ACAD10 Antibody (PACO05401)
Antibody SKU:
PACO05401
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:40000, IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from the Internal region of human ACAD-10.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
ACAD10; Acyl-CoA dehydrogenase family member 10; ACAD-10
UniProt Protein Function:
ACAD10: Acyl-CoA dehydrogenase only active with R- and S-2- methyl-C15-CoA. Belongs to the acyl-CoA dehydrogenase family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: EC 1.3.99.-; Mitochondrial; OxidoreductaseChromosomal Location of Human Ortholog: 12q24.12Cellular Component: mitochondrionMolecular Function: acyl-CoA dehydrogenase activity; FAD binding; hydrolase activity; transferase activity, transferring phosphorus-containing groups
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes (ACADs), which participate in the beta-oxidation of fatty acids in mitochondria. The encoded enzyme contains a hydrolase domain at the N-terminal portion, a serine/threonine protein kinase catlytic domain in the central region, and a conserved ACAD domain at the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Nov 2008]
