The TAL1 Antibody (CAB12927) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is highly specific to human TAL1 and has been validated for use in Western blot applications. By binding to the TAL1 protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for research in hematology and oncology.TAL1 is a key regulator of hematopoietic stem cell differentiation, playing a crucial role in blood cell formation and function. Dysregulation of TAL1 expression has been linked to hematologic malignancies such as T-cell acute lymphoblastic leukemia, making it a target of interest for cancer researchers.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Rat samples.
Product Name:
TAL1 Antibody
SKU:
CAB12927
Size:
20μL, 100μL
Reactivity:
Human, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
SCL, TCL5, tal-1, bHLHa17, TAL1
Positive Sample:
Jurkat, HT-29, Rat brain
Cellular Localization:
Nucleus.
Calculated MW:
34kDa
Observed MW:
50kDa
Enables several functions, including DNA-binding transcription factor activity; E-box binding activity; and histone deacetylase binding activity. Involved in several processes, including myeloid cell differentiation; positive regulation of cellular component organization; and positive regulation of erythrocyte differentiation. Located in chromatin and nucleoplasm. Part of transcription regulator complex. Implicated in acute lymphoblastic leukemia.
Purification Method
Affinity purification
Gene ID
6886
RRID
AB_2759773
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TAL1 Rabbit pAb (CAB12927) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
