The ACSM2A Antibody (CAB15563) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high specificity and sensitivity when used with human samples and is validated for use in Western blotting applications.ACSM2A, also known as Acyl-CoA synthetase medium-chain family member 2A, plays a crucial role in fatty acid metabolism by catalyzing the formation of acyl-CoA from medium-chain fatty acids. Dysregulation of ACSM2A has been linked to various metabolic disorders, making it a target of interest in research related to obesity, diabetes, and cardiovascular diseases.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.
Product Name:
ACSM2A Antibody
SKU:
CAB15563
Size:
20μL, 100μL
Reactivity:
Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
ACSM2, A-923A4.1, ACSM2A
Positive Sample:
Mouse kidney, Rat liver
Cellular Localization:
Mitochondrion Matrix.
Calculated MW:
64kDa
Observed MW:
64kDa
This gene encodes a mitochondrial acyl-coenzyme A synthetase that is specific for medium chain fatty acids. These enzymes catalyze fatty acid activation, the first step of fatty acid metabolism, through the transfer of acyl-CoA. These enzymes also participate in the glycine conjugation pathway in the detoxification of xenobiotics such as benzoate and ibuprofen. Expression levels of this gene in the kidney may be correlated with kidney function. This gene and its paralog ACSM2B (Gene ID: 348158), both present on chromosome 16, likely arose from a chromosomal duplication event.
Purification Method
Affinity purification
Gene ID
123876
RRID
AB_2762967
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using ACSM2A Rabbit pAb (CAB15563) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
