The ACTBL2 Monoclonal Antibody (PACO00366) is a valuable tool for researchers studying ACTBL2, an actin-binding protein crucial for cell motility and cytoskeleton organization. This antibody, produced in mice, is highly specific to human ACTBL2 and is validated for use in various applications including Western blot, immunofluorescence, and immunohistochemistry.ACTBL2, a member of the actin family, plays a key role in cell migration, cell division, and intracellular transport processes.
Its dysregulation has been associated with cancer progression, making it an important target for cancer research. The ACTBL2 Monoclonal Antibody enables researchers to study the expression and localization of ACTBL2 in different cell types, providing valuable insights into its function and potential as a therapeutic target in cancer treatment.
Antibody Name:
ACTBL2 Antibody
Antibody SKU:
PACO00366
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human, Mouse
Immunogen:
synthesized peptide derived from the Internal region of human Actin-Kappa.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
ACTBL2; Beta-actin-like protein 2; Kappa-actin
UniProt Protein Function:
ACTBL2: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Interacts with PFN1 and PFDN1. Belongs to the actin family.Protein type: Motility/polarity/chemotaxis; CytoskeletalChromosomal Location of Human Ortholog: 5q11.2Cellular Component: cytoplasm; cytoskeleton; extracellular spaceMolecular Function: ATP binding
