The ACTRT1 Antibody (PAC024739) is a highly specific tool for researchers studying ACTRT1, a protein involved in actin filament dynamics and cell motility. This polyclonal antibody, produced in rabbits, is optimized for use in various applications including Western blot and immunofluorescence. It recognizes the ACTRT1 protein in human samples, allowing for detailed analysis and detection in different cell types.ACTRT1, also known as actin-related protein T1, is a key player in cell movement and shape changes, making it a critical target for studies in cell biology and cancer research.
By understanding the function of ACTRT1, researchers can gain insights into mechanisms of cell migration and invasion, which are crucial processes in cancer metastasis. This antibody is an essential tool for investigating the roles of ACTRT1 in normal cellular processes and disease development.
Antibody Name:
ACTRT1 Antibody (PACO24739)
Antibody SKU:
PACO24739
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Actin-related protein T1 protein (201-376AA)
Immunohistochemistry of paraffin-embedded human colon tissue using PACO24739 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO24739 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human gastric cancer using PACO24739 at dilution of 1:100.
Background:
mitophagy in response to mitochondrial depolarization, positive regulation of defense response to virus by host, xenophagy
Synonyms:
Actin-related protein T1 (ARP-T1), ACTRT1, ARPT1
UniProt Protein Function:
ACTRT1: a protein related to the cytoskeletal protein beta-actin. This protein is a major component of the calyx in the perinuclear theca of mammalian sperm heads, and it therefore likely functions in spermatid formation. This gene is intronless and is similar to a related gene located on chromosome 1. A related pseudogene has also been identified approximately 75 kb downstream of this gene on chromosome X. [provided by RefSeq, May 2010]Protein type: CytoskeletalChromosomal Location of Human Ortholog: Xq25Cellular Component: cytoskeleton; cytoplasm
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein related to the cytoskeletal protein beta-actin. This protein is a major component of the calyx in the perinuclear theca of mammalian sperm heads, and it therefore likely functions in spermatid formation. This gene is intronless and is similar to a related gene located on chromosome 1. A related pseudogene has also been identified approximately 75 kb downstream of this gene on chromosome X. [provided by RefSeq, May 2010]
