The ADCY7 Polyclonal Antibody (PACO03392) is a valuable tool for researchers studying ADCY7, a key enzyme involved in signal transduction and cellular communication. This antibody, produced in rabbits, is specifically designed for use in immunohistochemistry and immunofluorescence applications. It specifically binds to the ADCY7 protein, allowing for accurate detection and analysis in a variety of cell types and tissues.ADCY7, also known as adenylate cyclase 7, plays a crucial role in generating the secondary messenger molecule cAMP, which is involved in various physiological processes such as cell growth, metabolism, and neurotransmission.
Dysregulation of ADCY7 has been implicated in diseases like cancer, diabetes, and neurological disorders, making it a compelling target for research.By utilizing the ADCY7 Polyclonal Antibody, researchers can gain valuable insights into the function and regulation of ADCY7, paving the way for the development of novel therapeutic strategies targeting this enzyme. Its high specificity and sensitivity make it an essential tool for studies aiming to unravel the complexities of cellular signaling pathways involving ADCY7.
Antibody Name:
ADCY7 Antibody
Antibody SKU:
PACO03392
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC, IF
Recommended Dilutions:
IHC:1:100-1:300, IF:1:200-1:1000
Species Reactivity:
Human, Mouse
Immunogen:
synthesized peptide derived from the Internal region of human A Cyclase VII.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
ADCY7; KIAA0037; Adenylate cyclase type 7; ATP pyrophosphate-lyase 7; Adenylate cyclase type VII; Adenylyl cyclase 7
UniProt Protein Function:
ADCY7: This is a membrane-bound, calcium-inhibitable adenylyl cyclase. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.Protein type: Adenylyl cyclase; EC 4.6.1.1; Lyase; Membrane protein, integral; Membrane protein, multi-pass; Nucleotide Metabolism - purine; Transporter; Transporter, aquaporin familyChromosomal Location of Human Ortholog: 16q12.1Cellular Component: integral to membrane; plasma membraneMolecular Function: adenylate cyclase activityBiological Process: activation of protein kinase A; adenylate cyclase activation; cAMP-mediated signaling; G-protein signaling, adenylate cyclase activating pathway; G-protein signaling, adenylate cyclase inhibiting pathway; positive regulation of cAMP biosynthetic process; renal water homeostasis
