The ADIPOR2 Antibody (CAB12777) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications.Adipor2 plays a key role in adiponectin signaling, which influences glucose and lipid metabolism, making it a significant target for research in obesity, diabetes, and metabolic diseases. By binding specifically to the Adipor2 protein, this antibody allows for the detection and analysis of Adipor2 expression in various cell types, making it an essential component for studies in metabolic disorders and related fields.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
ADIPOR2 Antibody
SKU:
CAB12777
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
PAQR2, ACDCR2, ADIPOR2
Positive Sample:
Mouse heart, Rat skeletal muscle
Cellular Localization:
Cell Membrane, Multi-Pass Membrane Protein.
Calculated MW:
44kDa
Observed MW:
44kDa
The adiponectin receptors, ADIPOR1 (MIM 607945) and ADIPOR2, serve as receptors for globular and full-length adiponectin (MIM 605441) and mediate increased AMPK (see MIM 602739) and PPAR-alpha (PPARA; MIM 170998) ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin (Yamauchi et al., 2003 [PubMed 12802337]).
Purification Method
Affinity purification
Gene ID
79602
RRID
AB_2759621
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from Mouse heart, using ADIPOR2 Rabbit pAb (CAB12777) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
Western blot analysis of lysates from Rat skeletal muscle, using ADIPOR2 Rabbit pAb (CAB12777) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
