The AHA1 Monoclonal Antibody (CAB9538) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, is highly specific and reactive with human samples, making it a valuable tool for studying the function and regulation of AHA1 in various biological processes.AHA1 is a co-chaperone protein that interacts with HSP90 to modulate its ATPase activity, thereby regulating the activity of HSP90 client proteins involved in processes such as cell signaling, protein folding, and cell cycle regulation. Understanding the role of AHA1 in these pathways is essential for unraveling its potential implications in diseases such as cancer, neurodegenerative disorders, and autoimmune conditions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
AHA1 Monoclonal Antibody
SKU:
CAB9538
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC1623
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
p38, AHA1, hAha1, C14orf3
Positive Sample:
HeLa, 293T, RD, Mouse brain, Rat brain
Cellular Localization:
Cytoplasm, Endoplasmic Reticulum, Cytosol.
Calculated MW:
38kDa
Observed MW:
42kDa
Enables ATPase activator activity; Hsp90 protein binding activity; and chaperone binding activity. Involved in positive regulation of ATPase activity. Located in cytosol.
Purification Method
Affinity purification
Gene ID
10598
RRID
AB_2863717
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using AHA1 Rabbit mAb (CAB9538) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
