Description
AKAP17A Antibody (PACO12146)
The AKAP17A Polyclonal Antibody (PAC012146) is a crucial tool for researchers studying AKAP17A, a key protein involved in intracellular signaling and protein scaffolding. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to AKAP17A, this antibody allows for the detection and analysis of the protein in various cell types, making it an essential reagent for studies in cell biology and signal transduction pathways.AKAP17A, also known as A-kinase anchor protein 17A, has been shown to play a role in the regulation of protein kinase A (PKA) signaling, as well as in the organization of macromolecular signaling complexes within cells.
Research into the function of AKAP17A is important for understanding how intracellular signaling pathways are coordinated and regulated, and how dysregulation of these pathways can contribute to diseases such as cancer, cardiovascular disorders, and neurological conditions.By utilizing the AKAP17A Polyclonal Antibody (PAC012146), researchers can gain valuable insights into the role of AKAP17A in cellular physiology and disease processes, ultimately leading to the development of novel therapeutic strategies targeting intracellular signaling pathways regulated by this important protein.
| Antibody Name: | AKAP17A Antibody (PACO12146) |
| Antibody SKU: | PACO12146 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Human SFRS17A |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | splicing factor, arginine/serine-rich 17A;SFRS17A;721P;CCDC133;CXYorf3;DXYS155E;MGC125365;MGC125366;MGC39904;XE7;XE7Y ; |
| UniProt Protein Function: | SFRS17A: Splice factor regulating alternative splice site selection for certain mRNA precursors. Mediates regulation of pre- mRNA splicing in a PKA-dependent manner. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:RNA splicing Chromosomal Location of Human Ortholog: Xp22.33 and Yp11.32 Cellular Component: cytoplasm; nuclear speck; nucleoplasm; nucleus Molecular Function:protein binding; protein kinase A binding Biological Process: regulation of RNA splicing |
| NCBI Summary: | This locus encodes a protein kinase A anchoring protein. The encoded protein is part of the spliceosome complex and is involved in the regulation of alternate splicing in some mRNA precursors. Alternatively spliced transcript variants have been identified for this gene.[provided by RefSeq, Sep 2010] |
| UniProt Code: | Q02040 |
| NCBI GenInfo Identifier: | 146291102 |
| NCBI Gene ID: | 8227 |
| NCBI Accession: | Q02040.2 |
| UniProt Secondary Accession: | Q02040,Q02832, Q2TB98, Q5JQ74, Q5JQ76, Q8N6U9, |
| UniProt Related Accession: | Q02040 |
| Molecular Weight: | 51,409 Da |
| NCBI Full Name: | A-kinase anchor protein 17A |
| NCBI Synonym Full Names: | A-kinase anchoring protein 17A |
| NCBI Official Symbol: | AKAP17AÂ Â |
| NCBI Official Synonym Symbols: | XE7; 721P; XE7Y; CCDC133; CXYorf3; PRKA17A; SFRS17A; AKAP-17A; DXYS155EÂ Â |
| NCBI Protein Information: | A-kinase anchor protein 17A |
| UniProt Protein Name: | A-kinase anchor protein 17A |
| UniProt Synonym Protein Names: | 721P; B-lymphocyte antigen; Protein XE7; Protein kinase A-anchoring protein 17A; PRKA17A; Splicing factor, arginine/serine-rich 17A |
| Protein Family: | A-kinase anchor protein |
| UniProt Gene Name: | AKAP17AÂ Â |
| UniProt Entry Name: | AK17A_HUMAN |
