The AMDHD2 polyclonal antibody (PAC015418) is a powerful tool for researchers studying the AMDHD2 protein, which plays a crucial role in cellular metabolism and energy production. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for Western blot applications.AMDHD2 is involved in the metabolism of amino acids, specifically histidine, and defects in this gene have been linked to metabolic disorders and neurological conditions. By detecting and analyzing the AMDHD2 protein in various cell types, researchers can gain insights into its function and potential therapeutic implications in metabolic diseases and neurological disorders.
With its high reactivity and specificity, the AMDHD2 polyclonal antibody is a valuable tool for researchers in the fields of biochemistry, metabolism, and neurobiology. Its ability to specifically target the AMDHD2 protein opens up new possibilities for understanding its role in health and disease, paving the way for future research and therapeutic interventions.
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15418(AMDHD2 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human lymphoma cancer tissue using PACO15418(AMDHD2 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200).
Background:
AMDHD2 (amidohydrolase domain containing 2), also known as putative N-acetylglucosamine-6-phosphate deacetylase or GlcNAc 6-P deacetylase, is a 409 amino acid, protein belonging to the NAGA family. AMDHD2 participates in N-acetylglucosamine-6-phosphate deacetylase and in hydrolase activities, acting on carbon-nitrogen bonds, but not peptide bonds.
Synonyms:
amidohydrolase domain containing 2
UniProt Protein Function:
AMDHD2: Belongs to the NagA family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Hydrolase; Carbohydrate Metabolism - amino sugar and nucleotide sugar; EC 3.5.1.25Chromosomal Location of Human Ortholog: 16p13.3Cellular Component: cytosol; nucleusMolecular Function: N-acetylglucosamine-6-phosphate deacetylase activity; protein bindingBiological Process: N-acetylglucosamine catabolic process; N-acetylneuraminate catabolic process; UDP-N-acetylglucosamine biosynthetic process
