The AMHR2 Monoclonal Antibody (CAB8813) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced using rabbit monoclonal technology, exhibits high specificity and sensitivity when used with human samples, making it an excellent choice for applications such as Western blotting and immunohistochemistry.AMHR2, also known as anti-Mullerian hormone receptor type 2, is essential for the proper functioning of the reproductive system, particularly in the development of male and female sex organs.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
AMHR2 Monoclonal Antibody
SKU:
CAB8813
Size:
20μL, 100μL
Reactivity:
Human
Clone Number:
ARC1313
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
AMHR, MRII, MISR2, MISRII, AMHR2
Positive Sample:
SKOV3, PC-3, K-562, SGC-7901
Cellular Localization:
Membrane, Single-Pass Type I Membrane Protein.
Calculated MW:
52kDa/63kDa
Observed MW:
60kDa
This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method
Affinity purification
Gene ID
269
RRID
AB_2863613
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using AMHR2 Rabbit mAb (CAB8813) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3min.
