The ANGPTL8 Polyclonal Antibody (CAB18133) is a high-quality antibody developed for reliable detection and analysis of target proteins. The antibody, produced in rabbits, offers high reactivity with human samples and has been validated for use in Western blot applications.ANGPTL8 is a novel protein that has been shown to control lipid metabolism by regulating triglyceride clearance and promoting fat storage in adipose tissue. It is also involved in the regulation of glucose metabolism and insulin sensitivity, making it a potential target for the treatment of metabolic disorders such as obesity and diabetes.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
ANGPTL8 Polyclonal Antibody
SKU:
CAB18133
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
RIFL, TD26, PRO1185, PVPA599, C19orf80, ANGPTL8
Positive Sample:
HepG2, THP-1(Negative control)
Cellular Localization:
Extracellular Region.
Calculated MW:
22kDa
Observed MW:
24kDa
Predicted to enable hormone activity. Involved in regulation of lipid metabolic process and triglyceride homeostasis. Acts upstream of or within positive regulation of protein processing and regulation of lipoprotein metabolic process. Located in extracellular region.
Purification Method
Affinity purification
Gene ID
55908
RRID
AB_2861924
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using ANGPTL8 Rabbit pAb (CAB18133) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
