The ANP32C Monoclonal Antibody (PAC001357) is a valuable tool for researchers studying ANP32C, a protein involved in various cellular processes such as apoptosis, cellular proliferation, and transcriptional regulation. This antibody, produced using hybridoma technology, is highly specific for human ANP32C and has been validated for use in immunofluorescence and immunohistochemistry applications.ANP32C, also known as acidic nuclear phosphoprotein 32 family member C, plays a crucial role in cell cycle progression and DNA damage response pathways.
Dysregulation of ANP32C has been implicated in various diseases, including cancer and neurodegenerative disorders. The ANP32C Monoclonal Antibody enables researchers to study the expression and localization of ANP32C in different cell types and tissues, providing insights into its functions and potential therapeutic targets. By understanding the role of ANP32C in disease pathogenesis, novel treatment strategies may be developed to target these conditions effectively.
Antibody Name:
ANP32C Antibody
Antibody SKU:
PACO01357
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human PP32R1.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
ANP32C; PP32R1; Acidic leucine-rich nuclear phosphoprotein 32 family member C; Phosphoprotein 32-related protein 1; Tumorigenic protein pp32r1
UniProt Protein Function:
ANP32C: Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is divergent between PP32 and the protein encoded by this gene. This gene does not contain introns. [provided by RefSeq, Jul 2008]Chromosomal Location of Human Ortholog: 4q32.3
UniProt Protein Details:
NCBI Summary:
Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is divergent between PP32 and the protein encoded by this gene. This gene does not contain introns. [provided by RefSeq, Jul 2008]
