The Anti-AFP Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0239) is a cutting-edge tool for researchers studying AFP (alpha-fetoprotein), a key biomarker often associated with various cancers, including liver cancer. This antibody, developed using advanced chimeric recombinant technology, offers superior sensitivity and specificity in detecting AFP in human samples.AFP is a glycoprotein expressed at high levels in fetal tissue and certain cancer cells, making it a valuable target for cancer diagnostics and research. The Anti-AFP Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0239) precisely targets AFP, enabling precise and reliable detection in immunoassays, immunohistochemistry, and other applications.
This antibody is an essential tool for investigating AFP's role in cancer development, progression, and response to treatment. Its exceptional performance and specificity make it a must-have for researchers seeking to further understand the mechanisms underlying AFP-associated cancers and develop targeted diagnostic and therapeutic strategies.
SKU:
HDAB0239
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC281
Synonyms:
AFPD, FETA, HPAFP
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
