The Anti-B7-H5 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0248) is a cutting-edge tool for researchers studying B7-H5, a protein involved in immune regulation and modulation of immune responses. This antibody, produced using innovative chimeric recombinant technology in rabbits, shows high specificity and sensitivity in detecting B7-H5 in human samples, making it ideal for use in various research applications such as Western blot analysis.B7-H5, also known as VISTA (V-domain Ig suppressor of T cell activation), is a key checkpoint molecule that plays a crucial role in regulating T cell responses and immune tolerance.
Its involvement in immune checkpoint pathways makes it a promising target for therapeutic interventions in diseases such as cancer, autoimmune disorders, and inflammatory conditions. The Anti-B7-H5 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0248) is a valuable tool for investigating the function and expression of B7-H5 in different cell types, offering new insights into immune regulation and potential therapeutic strategies.
SKU:
HDAB0248
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC299
Synonyms:
B7-H5, B7H5, C10orf54, DD1alpha, Dies1, GI24, PD-1H, PP2135, SISP1, VISTA
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
Immunoregulatory receptor which inhibits the T-cell response (PubMed:24691993). May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (By similarity). May stimulate MMP14-mediated MMP2 activation (PubMed:20666777).
