The Anti CCR4 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0246) offered by Assay Genie is a powerful tool for researchers studying the CCR4 protein, a cell surface molecule involved in immune response regulation. This antibody, developed using advanced recombinant technology, demonstrates high specificity and sensitivity in detecting CCR4 in human samples. Validated for use in Western blot applications, it allows for precise and accurate analysis of CCR4 expression in various cell types.CCR4, a chemokine receptor known for its role in immune cell migration and activation, is a key player in various immune-related processes, including inflammation and immune surveillance.
Dysregulation of CCR4 has been implicated in diseases such as cancer, autoimmune disorders, and inflammatory conditions, highlighting its importance as a therapeutic target. By enabling the precise detection and analysis of CCR4, this antibody facilitates research into the mechanisms underlying these diseases and the development of novel treatment strategies.For researchers interested in immunology, cancer biology, and inflammatory diseases, the Anti CCR4 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0246) is an essential tool for advancing their understanding of CCR4 function and its implications in health and disease.
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.
