The Anti-CHX10 Antibody (CAB19828) is a valuable tool for researchers studying the CHX10 protein, also known as Visual System Homeobox 2 (VSX2), which plays a crucial role in eye development and retinal cell differentiation. This polyclonal antibody, produced in rabbits, is highly specific to human samples and has been validated for use in applications such as immunofluorescence and immunohistochemistry.CHX10 is essential for the proper formation of the eye during embryonic development, as well as for maintaining the function of retinal cells in the adult eye. Dysregulation of CHX10 expression has been linked to various eye disorders, making it a target of interest in ophthalmology research.
This antibody binds specifically to CHX10, allowing for its visualization and analysis in a variety of cell and tissue types.Researchers in the fields of developmental biology, ophthalmology, and vision science will find the Anti-CHX10 Antibody (CAB19828) to be a valuable tool for studying the intricate processes involved in eye development and function. By understanding the role of CHX10 in normal and diseased states, this antibody can contribute to the development of potential therapies for eye-related conditions.
Product Name:
CHX10 Rabbit Monoclonal Antibody
SKU:
CAB19828
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 262-361 of human CHX10 (P58304).
Mouse spinal cord, Mouse brain, Rat spinal cord, Rat brain
Conjugate:
Unconjugated
Cellular Localization:
Nucleus
Calculated MW:
39kDa
Observed MW:
43kDa
This gene encodes a homeobox protein originally described as a retina-specific transcription factor. Mutations in this gene are associated with microphthalmia, cataracts and iris abnormalities.
Purification Method:
Affinity purification
Gene ID:
338917
Clone Number:
ARC2354
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various lysates, using CHX10 Rabbit mAb (CAB19828) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
