The DLGAP3 Polyclonal Antibody (CAB20386) is a valuable tool for researchers studying DLGAP3, a member of the membrane-associated guanylate kinase (MAGUK) family of proteins involved in synaptic function. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. It specifically binds to the DLGAP3 protein, facilitating analysis and detection in various cell types, making it ideal for neurobiology and neuroscience research.DLGAP3 plays a crucial role in regulating synaptic plasticity and neurotransmission, making it an important target for investigation in conditions related to neuronal function and communication.
Research on DLGAP3 may provide insights into neurological disorders such as autism, schizophrenia, and Alzheimer's disease, where dysfunction in synaptic transmission is implicated. Understanding the function of DLGAP3 could potentially lead to the development of novel therapeutic strategies targeting synaptic dysfunction in these disorders.
Product Name:
DLGAP3 Rabbit Polyclonal Antibody
SKU:
CAB20386
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DLGAP3 (NP_001073887.1).
Predicted to enable PDZ domain binding activity; molecular adaptor activity; and scaffold protein binding activity. Predicted to be involved in protein-containing complex assembly and regulation of postsynaptic neurotransmitter receptor activity. Predicted to be located in synapse. Predicted to be part of postsynaptic density. Predicted to be active in several cellular components, including cholinergic synapse; glutamatergic synapse; and neuromuscular junction.
Purification Method:
Affinity purification
Gene ID:
58512
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse brain, using DLGAP3 Rabbit pAb (CAB20386) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
