The EXOSC7 Monoclonal Antibody (CAB0501) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, specifically targets human samples and has been validated for use in Western blot applications.EXOSC7 is essential for the stability and function of the exosome complex, which plays a crucial role in regulating gene expression and maintaining cellular homeostasis. Dysregulation of EXOSC7 has been linked to various diseases, including cancer and neurodegenerative disorders, making it a promising therapeutic target for further investigation.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
EXOSC7 Monoclonal Antibody
SKU:
CAB0501
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Clone Number:
ARC2510
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
p8, EAP1, RRP42, Rrp42p, hRrp42p, EXOSC7
Positive Sample:
HepG2, A-431, NIH/3T3, K-562
Cellular Localization:
Cytoplasm, Nucleus, Nucleolus.
Calculated MW:
32kDa
Observed MW:
37kDa
Predicted to enable 3'-5'-exoribonuclease activity and RNA binding activity. Predicted to be involved in RNA metabolic process. Part of exosome (RNase complex).
Purification Method
Affinity purification
Gene ID
23016
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using EXOSC7 Rabbit mAb (CAB0501) at 1:1000 dilution incubated overnight at 4°C. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180 s.
