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Anti-GALNT4 Antibody (CAB4243)

SKU:
CAB4243
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
GALNT4
GALNAC-T4
GALNACT4
$167 - $503
Frequently bought together:

Description

Product Name:GALNT4 Rabbit pAb
Product Code:CAB4243
Size:50uL, 100uL
Synonyms:GALNT4, GALNAC-T4, GALNACT4
Applications:WB
Reactivity:Human, Rat
Host Species:Rabbit
Immunogen:Recombinant protein of human GALNT4.
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human, Rat
Positive Samples:HeLa, Rat brain
Immunogen:Recombinant protein of human GALNT4.
Purification Method:Affinity purification
Storage:Store at 4°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:8693
Uniprot:Q8N4A0
Cellular Location:Golgi apparatus membrane, Single-pass type II membrane protein
Calculated MW:45kDa/66kDa
Observed MW:67KDa
UniProt Protein Function:GALNT4: an enzyme that catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. A single-pass type II membrane protein that localizes to the Golgi apparatus membrane.
UniProt Protein Details:

Protein type:Glycan Metabolism - O-glycan biosynthesis; Membrane protein, integral; EC 2.4.1.41; Transferase

Chromosomal Location of Human Ortholog: 12q21.33

Cellular Component: Golgi membrane; Golgi apparatus; perinuclear region of cytoplasm; integral to membrane

Molecular Function:metal ion binding; polypeptide N-acetylgalactosaminyltransferase activity; carbohydrate binding

Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; O-glycan processing; carbohydrate metabolic process; post-translational protein modification

NCBI Summary:This locus represents naturally occurring transcripts that splice the 5' exons of the POC1B (POC1 centriolar protein homolog B) gene on chromosome 12 to the GALNT4 (UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4) gene, which is located within a POC1B intron. Alternative splicing results in two transcript variants, one of which encodes a fusion isoform that shares sequence identity with the products of each individual gene. [provided by RefSeq, Dec 2010]
UniProt Code:Q8N4A0
NCBI GenInfo Identifier:338817878
NCBI Gene ID:100528030
NCBI Accession:Q8N4A0.2
UniProt Secondary Accession:Q8N4A0,O00208, B2R775, B4DMX6,
Molecular Weight:578
NCBI Full Name:Polypeptide N-acetylgalactosaminyltransferase 4
NCBI Synonym Full Names:POC1B-GALNT4 readthrough
NCBI Official Symbol:POC1B-GALNT4  
NCBI Protein Information:POC1B-GALNT4 protein; POC1B-GALNT4 fusion
UniProt Protein Name:Polypeptide N-acetylgalactosaminyltransferase 4
UniProt Synonym Protein Names:Polypeptide GalNAc transferase 4; GalNAc-T4; pp-GaNTase 4; Protein-UDP acetylgalactosaminyltransferase 4; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4
Protein Family:Polypeptide N-acetylgalactosaminyltransferase
UniProt Gene Name:GALNT4  
UniProt Entry Name:GALT4_HUMAN

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