The GPX5 Polyclonal Antibody (CAB1075) is designed for research involving GPX5, an enzyme involved in protecting cells from oxidative damage by reducing hydrogen peroxide and lipid hydroperoxides. The antibody, raised in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. It binds to the GPX5 protein, allowing for detection and analysis in various cell types, making it ideal for studies in oxidative stress and cancer research.GPX5, also known as glutathione peroxidase 5, is a crucial enzyme in the defense against oxidative stress and is involved in maintaining cellular redox balance.
Its role in protecting cells from oxidative damage makes it a key player in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. Therefore, understanding the function of GPX5 is essential for developing therapies that target oxidative stress-related conditions and improve overall cell health.
Product Name:
GPX5 Rabbit Polyclonal Antibody
SKU:
CAB1075
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human GPX5 (NP_003987.2).
This gene belongs to the glutathione peroxidase family. It is specifically expressed in the epididymis in the mammalian male reproductive tract, and is androgen-regulated. Unlike several other characterized glutathione peroxidases, this enzyme is not a selenoprotein, lacking the selenocysteine residue. Thus, it is selenium-independent, and has been proposed to play a role in protecting the membranes of spermatozoa from the damaging effects of lipid peroxidation and/or preventing premature acrosome reaction. Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
2880
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GPX5 antibody (CAB1075).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
