The Anti-GUCY2C Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0255) is a cutting-edge tool for researchers studying GUCY2C, a cell surface receptor known for its role in intestinal homeostasis and tumorigenesis. This antibody, developed from rabbit monoclonal cells, exhibits high specificity and sensitivity in detecting GUCY2C in human samples, making it an essential resource for Western blot and immunohistochemistry applications.GUCY2C, also known as guanylate cyclase C, is a key player in the regulation of intestinal fluid and electrolyte transport, as well as in gastrointestinal tumorigenesis.
By targeting GUCY2C, researchers can explore its mechanisms of action in both normal and diseased tissues, offering insights into potential therapeutic interventions for gastrointestinal disorders and cancers.With its ability to bind specifically to GUCY2C, the Anti-GUCY2C Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0255) provides a valuable tool for investigating the function and expression of GUCY2C in various experimental models. Its applications in immunology and cancer research make it an indispensable asset for scientific inquiries into the role of GUCY2C in health and disease.
SKU:
HDAB0255
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC387
Synonyms:
DIAR6, GC-C, GUC2C, MECIL, MUCIL, STAR
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive).
