The Anti-ICAM-1 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0250) is a valuable tool for research involving ICAM-1, a cell adhesion molecule involved in inflammation and immune responses. This antibody, generated in rabbits, shows high reactivity with human samples and has been validated for use in various applications, including Western blotting.ICAM-1, also known as intercellular adhesion molecule-1, plays a crucial role in cell-cell interactions and recruitment of immune cells to sites of inflammation. Its upregulation is often seen in various inflammatory conditions, making it a key target for research in immunology and inflammation-related diseases.
The Anti-ICAM-1 antibody binds specifically to the ICAM-1 protein, allowing for precise detection and analysis in different cell types.Research utilizing this antibody can provide deeper insights into the mechanisms of inflammation and immune response regulation, particularly in the context of diseases like cancer, autoimmune disorders, and inflammatory conditions. By understanding the role of ICAM-1, researchers can further develop targeted therapies for modulating immune responses and treating associated disorders.
SKU:
HDAB0250
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC367
Synonyms:
ICAM1,BB2,CD54,P3.58
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor.
