The IGHD Monoclonal Antibody (CAB19708) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the IGHG protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an excellent tool for studies in immunology and cancer research.IGHD, also known as immunoglobulin heavy constant delta, plays a crucial role in immune regulation by modulating immune responses and antibody production. Its involvement in immune function makes it a valuable target for research into various diseases, including cancer, autoimmune disorders, and inflammatory conditions.
This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
IGHD Monoclonal Antibody
SKU:
CAB19708
Size:
20μL, 100μL
Reactivity:
Human
Clone Number:
ARC2240
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Positive Sample:
Human plasma
Cellular Localization:
Blood Microparticle, External Side Of Plasma Membrane, Extracellular Exosome, Extracellular Space, Immunoglobulin Complex, Circulating, Plasma Membrane.
Calculated MW:
42kDa
Observed MW:
55kDa
Predicted to enable antigen binding activity and immunoglobulin receptor binding activity. Involved in positive regulation of interleukin-1 production. Located in blood microparticle and extracellular exosome.
Purification Method
Affinity purification
Gene ID
3495
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from Human plasma, using IGHD Rabbit mAb (CAB19708) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
Immunohistochemistry analysis of paraffin-embedded Human tonsil using IGHD Rabbit mAb (CAB19708) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Tris/EDTA Buffer (pH 9.0) prior to IHC staining.
