The Anti-IL-6 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0263) is a cutting-edge tool for researchers studying IL-6, a key cytokine involved in inflammation and immune responses. This antibody, produced in rabbits, is highly specific and sensitive for detecting IL-6 in human samples, making it a valuable asset for various research applications.IL-6 is a multifunctional cytokine that plays a crucial role in the regulation of immune responses, inflammation, and various diseases, including cancer, autoimmune disorders, and inflammatory conditions. The Anti-IL-6 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0263) binds specifically to IL-6, allowing for accurate detection and analysis in a wide range of cell types.
By utilizing this antibody, researchers can gain valuable insights into the role of IL-6 in disease pathogenesis and progression, as well as potential therapeutic targets for modulating IL-6 signaling. Its high specificity and sensitivity make it an essential tool for studies in immunology, oncology, and inflammatory diseases, offering new opportunities for advancing our understanding of IL-6 biology.
SKU:
HDAB0263
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC419
Synonyms:
IL6, Interleukin-6, BSF2, HSF, IFNB2
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants.
