The Anti-IL5RA Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0261) is a powerful tool for research involving IL5RA, a cell surface receptor that plays a key role in the immune response. This antibody, developed using cutting-edge technology, exhibits high specificity and sensitivity towards IL5RA in human samples, making it an ideal choice for various research applications including Western blotting and immunohistochemistry.IL5RA is known for its involvement in allergic reactions and inflammatory processes, making it a target of interest in studies related to immunology and cancer research.
By specifically targeting IL5RA, researchers can gain valuable insights into its functions and potential therapeutic implications in diseases such as asthma, allergy, and certain types of cancer.The Anti-IL5RA Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0261) offers researchers a reliable tool for studying the role of IL5RA in immune regulation and disease pathogenesis. Its high reactivity and specificity make it a valuable asset in advancing our understanding of IL5RA biology and potential therapeutic interventions.
SKU:
HDAB0261
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC393
Synonyms:
IL5Ra,CD125,IL-5 R alpha
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.
