The IMP3 Polyclonal Antibody (CAB3508) is a valuable tool for researchers studying IMP3, a protein associated with aggressive cancer behavior and poor patient prognosis. This antibody, produced in rabbits, has high specificity for human samples and has been validated for use in immunohistochemistry and western blotting applications. By targeting IMP3, researchers can investigate its role in cancer development and progression, providing important insights for potential diagnostic and therapeutic strategies.IMP3, also known as insulin-like growth factor II mRNA-binding protein 3, is a biomarker for various cancers, including pancreatic, colorectal, and lung cancers. Its overexpression has been linked to tumor growth, metastasis, and resistance to therapy, making it a promising target for cancer research.
By studying IMP3 expression and function, researchers can gain a better understanding of its involvement in cancer pathogenesis, potentially leading to the development of novel treatment approaches.In conclusion, the IMP3 Polyclonal Antibody (CAB3508) is a reliable tool for investigating the role of IMP3 in cancer biology. Its specificity and sensitivity make it suitable for a wide range of research applications, providing valuable data for advancing our knowledge of cancer biology and potentially identifying new therapeutic targets.
Product Name:
IMP3 Rabbit Monoclonal Antibody
SKU:
CAB3508
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 2-194 of human IMP3 (O00425).
The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.
Purification Method:
Affinity purification
Gene ID:
10643
Clone Number:
ARC0792
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using IMP3 Rabbit mAb (CAB3508) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
