The Anti-M-CSF Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0275) is a highly specific and sensitive tool for researchers studying the Macrophage Colony-Stimulating Factor (M-CSF) pathway. M-CSF is a key cytokine involved in the differentiation and proliferation of macrophages, as well as the regulation of immune responses.This antibody, produced in rabbits, has been rigorously validated for use in a variety of applications, including Western blot, immunohistochemistry, and flow cytometry. Its high affinity for M-CSF makes it an excellent choice for detecting and quantifying M-CSF levels in a range of sample types, including cell lysates and tissue sections.
By targeting M-CSF, researchers can gain valuable insights into the role of macrophages in various physiological and pathological processes, such as inflammation, tissue repair, and cancer progression. The Anti-M-CSF Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0275) is a valuable tool for advancing our understanding of M-CSF signaling pathways and developing potential therapeutic strategies for diseases related to macrophage dysfunction.
SKU:
HDAB0275
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC437
Synonyms:
CSF-1, MCSF
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants.
