The Menin Monoclonal Antibody (CAB3395) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in mice, exhibits strong reactivity towards human samples and has been validated for use in various applications such as immunohistochemistry and immunofluorescence.Menin plays a crucial role in the development and progression of multiple endocrine neoplasia type 1 (MEN1) syndrome, a hereditary cancer syndrome characterized by tumors in multiple endocrine glands.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
Menin Monoclonal Antibody
SKU:
CAB3395
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC1968
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
MEAI, SCG2, Menin
Positive Sample:
HeLa, HCT 116, Hep G2, NIH/3T3, Mouse lung, Mouse brain
Cellular Localization:
Nucleus.
Calculated MW:
68kDa
Observed MW:
72kDa
This gene encodes menin, a tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. Menin is a scaffold protein that functions in histone modification and epigenetic gene regulation. It is thought to regulate several pathways and processes by altering chromatin structure through the modification of histones.
Purification Method
Affinity purification
Gene ID
4221
RRID
AB_2863051
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using Menin Rabbit mAb (CAB3395) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
