The MNX1/HB9/HLXB9 Antibody (CAB20537) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in mouse, is highly specific to human samples and has been validated for use in immunohistochemistry and Western blot applications.MNX1/HB9/HLXB9 is a transcription factor essential for the differentiation of motor neurons in the spinal cord, making it a key player in the development of the nervous system. Dysregulation of this protein has been linked to motor neuron diseases such as spinal muscular atrophy and amyotrophic lateral sclerosis, highlighting its importance in neurodegenerative disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
MNX1/HB9/HLXB9 Antibody
SKU:
CAB20537
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
HB9, HLXB9, SCRA1, HOXHB9, MNX1/HB9/HLXB9
Positive Sample:
HeLa, Mouse thymus, Rat liver
Cellular Localization:
Cytosol, Nucleolus, Nucleoplasm, Nucleus.
Calculated MW:
41kDa
Observed MW:
55kDa
This gene encodes a nuclear protein, which contains a homeobox domain and is a transcription factor. Mutations in this gene result in Currarino syndrome, an autosomic dominant congenital malformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
3110
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using MNX1/HB9/HLXB9 Rabbit pAb (CAB20537) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
Western blot analysis of lysates from Rat liver, using MNX1/HB9/HLXB9 Rabbit pAb (CAB20537) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 180s.
