Description
Anti-Mouse IFNß In Vivo Antibody - Low Endotoxin
Introducing the Anti-Mouse IFNγ In Vivo Antibody - Low Endotoxin from Assay Genie, a highly specific monoclonal antibody tailored for in vivo applications. This antibody targets the Interferon gamma (IFNγ) protein, pivotal in immune response modulation, making it indispensable for research in immunology and related fields. With a rat IgG1 isotype, it guarantees high purity and low endotoxin levels (<1.0 EU/mg), making it perfect for ELISA, flow cytometry, immunohistochemistry, and additional assays.
Available in various sizes, it is formulated in phosphate-buffered saline to ensure stability and efficacy. Elevate your research with this dependable and versatile antibody. IFNγ, a crucial cytokine produced by T-cells and natural killer cells, plays a central role in innate and adaptive immunity. It activates macrophages, enhances antigen presentation, and modulates the expression of numerous immune regulatory genes, hence being critical in defense against pathogens and tumors.
| Product Name: | Anti-Mouse IFNβ In Vivo Antibody - Low Endotoxin |
| Product Code: | IVMB0171 |
| Size: | 1mg, 5mg, 25mg, 50mg, 100mg |
| Clone: | HDβ-4A7 |
| Protein: | IFN-beta |
| Product Type: | Monoclonal Antibody |
| Synonyms: | IFN-b, IFN-beta, Type-1 interferon, Clone HDb-4A7 |
| Isotype: | Mouse IgG2a |
| Reactivity: | Mouse |
| Immunogen: | Plasmid DNA encoding murine IFNb |
| Applications: | B, FA, N, WB |
| Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Endotoxin Level: | < 1.0 EU/mg as determined by the LAL method |
| Purity: | ≥95% monomer by analytical SEC >95% by SDS Page |
| Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
| Storage and Handling: | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
| Applications: | B, FA, N, WB |
| Reactivity: | Mouse |
| Host Species: | Mouse |
| Specificity: | Mouse Anti-Mouse Interferon-beta (IFN-β) (Clone HDβ-4A7) recognizes an epitope on Mouse IFN-β and binds specifically to murine IFNβ and does not bind murine IFNg or several different IFNa species (a-1,4,5 or 13); HDb-4A7 binds both recombinant and natural forms. This antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
| Immunogen: | Plasmid DNA encoding murine IFNb |
| Concentration: | ≥ 5.0 mg/ml |
| Endotoxin Level: | < 1.0 EU/mg as determined by the LAL method |
| Purity: | ≥95% monomer by analytical SEC >95% by SDS Page |
| Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
| Storage and Handling: | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
| Technical Datasheet: | View |
| Protein: | IFN-beta |
| Research Area: | Apoptosis, Cell Biology, Cell Death, Signal Transduction, Tumor Suppressors |
