The NPAS3 Antibody (CAB20561) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for Western blotting experiments.NPAS3 is known for its involvement in regulating the expression of genes related to neurodevelopment and synaptic plasticity. Dysregulation of NPAS3 has been linked to various neurological disorders, including schizophrenia and bipolar disorder.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Rat samples.
Product Name:
NPAS3 Antibody
SKU:
CAB20561
Size:
20μL, 100μL
Reactivity:
Human, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
MOP6, PASD6, bHLHe12, NPAS3
Positive Sample:
HepG2, MCF7, C6, SH-SY5Y, U-251MG, U-87MG
Cellular Localization:
Nucleoplasm.
Calculated MW:
101kDa
Observed MW:
105kDa
This gene encodes a member of the basic helix-loop-helix and PAS domain-containing family of transcription factors. The encoded protein is localized to the nucleus and may regulate genes involved in neurogenesis. Chromosomal abnormalities that affect the coding potential of this gene are associated with schizophrenia and cognitive disability. Alternate splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
64067
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using NPAS3 Rabbit pAb (CAB20561) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
