The Oxytocin Receptor Monoclonal Antibody (CAB19740) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is validated for use in Western blot applications and is highly reactive with human samples. It binds specifically to the oxytocin receptor protein, enabling accurate detection and analysis in different cell types.The oxytocin receptor is a G-protein coupled receptor that plays a crucial role in mediating the effects of oxytocin, a hormone known for its role in bonding, trust, and social behavior. Dysregulation of the oxytocin receptor has been implicated in various neuropsychiatric disorders such as autism, schizophrenia, and anxiety disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
Oxytocin Receptor Monoclonal Antibody
SKU:
CAB19740
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC2266
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:
LLLA LSGN ACVL LALR TTRQ KHSR LFFF MKHL SIAD LVVA VFQV LPQL LWDI TFRF YGPD LLCR LVKY LQVV GMFA STYL LLLM SLDR CLAI CQPL RSLR R
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:1000 - 1:2000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
OTR, OT-R, Oxytocin Receptor
Positive Sample:
HeLa, Jukat, SW480, Mouse brain, Rat brain
Cellular Localization:
Cell Membrane.
Calculated MW:
43kDa
Observed MW:
46kDa
The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition.
Purification Method
Affinity purification
Gene ID
5021
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using Oxytocin Receptor Rabbit mAb (CAB19740) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
Western blot analysis of lysates from Rat brain using Oxytocin Receptor Rabbit mAb (CAB19740) at 1:1000 dilution incubated overnight at 4℃. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60 s.
