The PAX9 Monoclonal Antibody (CAB19741) is a high-quality antibody developed for reliable detection and analysis of target proteins. This polyclonal antibody, generated in rabbits, exhibits strong reactivity with human samples and is validated for use in various applications, including Western blotting and immunohistochemistry.PAX9 is essential for the formation and differentiation of different cell types during embryonic development, making it a key player in various developmental processes. Research has shown that mutations in the PAX9 gene are linked to dental anomalies and craniofacial abnormalities, highlighting the importance of studying its function in both normal and pathological conditions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
PAX9 Monoclonal Antibody
SKU:
CAB19741
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC2267
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
STHAG3, PAX9
Positive Sample:
PC-3, Mouse stomach, Mouse thymus, Rat lung, Rat stomach
Cellular Localization:
Nucleolus, Nucleoplasm.
Calculated MW:
36kDa
Observed MW:
38kDa
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. Mice lacking this gene exhibit impaired development of organs, musculature and the skeleton, including absent and abnormally developed teeth, and neonatal lethality. Mutations in the human gene are associated with selective tooth agenesis-3.
Purification Method
Affinity purification
Gene ID
5083
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using PAX9 Rabbit mAb (CAB19741) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
