![Anti-Phospho-GSK3 (alpha + beta) (Tyr279/Tyr216) [R47-6P-9] Monoclonal Antibody (AGMB05097)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/608x608/products/276382/667281/Assay_Genie_1000px_logo_2_1__57675.1769513940.jpg?c=2 "Anti-Phospho-GSK3 (alpha + beta) (Tyr279/Tyr216) [R47-6P-9] Monoclonal Antibody (AGMB05097)"){kind=logo}
![Anti-Phospho-GSK3 (alpha + beta) (Tyr279/Tyr216) [R47-6P-9] Monoclonal Antibody (AGMB05097)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/1280x1280/products/276382/667281/Assay_Genie_1000px_logo_2_1__57675.1769513940.jpg?c=2&imbypass=on "Anti-Phospho-GSK3 (alpha + beta) (Tyr279/Tyr216) [R47-6P-9] Monoclonal Antibody (AGMB05097)"){kind=logo}
Description
| Product Name: | Anti-Phospho-GSK3 (alpha + beta) (Tyr279/Tyr216) [R47-6P-9] Monoclonal Antibody |
| SKU: | AGMB05097 |
| Size: | 20μL, 50μL, 100μL |
| Reactivity: | Human, Mouse, Rat |
| Clone Number: | R47-6P-9 |
| Conjugate: | Unconjugated |
| Immunogen: | A synthesized peptide derived from human Phospho-GSK3 (alpha + beta) (Y216 + Y279). | ||||||||
| Tested Applications: | WB IHC-P ICC/IF IP | ||||||||
| Recommended Dilution: |
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| Synonyms: | GSK3α/β, Serine/threonine-protein kinase GSK3A, Serine/threonine-protein kinase GSK3B |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Modification: | Phosphorylated |
| Calculated MW: | 51kDa |
| Observed MW: | 51kDa |
Constitutively active protein kinase that negatively regulates glucose homeostasis, Wnt signaling, transcription factors, and microtubules through phosphorylation of multiple substrates including glycogen synthase and β-catenin. Plays key roles in insulin signaling, neuronal polarity, axon outgrowth, apoptosis regulation, and Alzheimer’s disease-associated amyloid processing.
| Purification Method: | Affinity Chromatography |
| Gene ID: | 2931 |
| Buffer: | 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide, 50% glycerol. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
