The Anti-PIK3IP1 Antibody (CAB20650) is a key tool for researchers studying PIK3IP1, a crucial regulatory molecule in the PI3K/AKT signaling pathway. This polyclonal antibody, generated in rabbits, is highly specific to human PIK3IP1 and has been validated for use in Western blot applications.PIK3IP1, also known as Phosphoinositide-3-Kinase Interacting Protein 1, plays a critical role in negatively regulating PI3K signaling, which is essential for cell growth, proliferation, and survival. Dysregulation of the PI3K pathway is implicated in a variety of diseases, including cancer, diabetes, and immune disorders.
By targeting PIK3IP1, researchers can gain insights into the intricate mechanisms of the PI3K pathway and potentially identify novel therapeutic targets for diseases associated with PI3K dysregulation. The Anti-PIK3IP1 Antibody is a valuable tool for investigating the role of PIK3IP1 in disease pathogenesis and developing targeted therapies for precision medicine approaches.
Product Name:
PIK3IP1 Polyclonal Antibody
SKU:
CAB20650
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-160 of human PIK3IP1 (NP_443112.2).
Enables phosphatidylinositol 3-kinase catalytic subunit binding activity. Involved in negative regulation of phosphatidylinositol 3-kinase activity and negative regulation of phosphatidylinositol 3-kinase signaling. Predicted to be located in plasma membrane. Predicted to be integral component of membrane.
Purification Method:
Affinity purification
Gene ID:
113791
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from SH-SY5Y cells, using PIK3IP1 Rabbit pAb (CAB20650) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
