The PITX3 Monoclonal Antibody (CAB19261) is a high-quality antibody developed for reliable detection and analysis of target proteins. The antibody, produced in mice, shows high specificity and sensitivity towards human samples and is suitable for use in various applications including immunofluorescence and immunohistochemistry.PITX3 is known for its crucial role in the development of midbrain dopaminergic neurons, making it a key player in the pathogenesis of Parkinson's disease and other neurodegenerative disorders. Research on PITX3 can provide insights into the mechanisms underlying neuronal differentiation and function, offering potential targets for therapeutic interventions aimed at treating neurological conditions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
PITX3 Monoclonal Antibody
SKU:
CAB19261
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC2429
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
ASMD, ASOD, PTX3, ASGD1, CTPP4, CTRCT11, PITX3
Positive Sample:
C6, SH-SY5Y, U-87MG, Mouse eye
Cellular Localization:
Nucleus.
Calculated MW:
32kDa
Observed MW:
32kDa
This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family act as transcription factors. This protein is involved in lens formation during eye development. Mutations of this gene have been associated with anterior segment mesenchymal dysgenesis and congenital cataracts.
Purification Method
Affinity purification
Gene ID
5309
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using PITX3 Rabbit mAb (CAB19261) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
