The Anti-PRDM9 Antibody (CAB20428) is a polyclonal antibody designed for research involving PRDM9, a protein involved in meiotic recombination and DNA binding. This antibody, raised in rabbits, is highly specific to human PRDM9 samples and is validated for use in various applications such as Western blot and immunohistochemistry.PRDM9 is a key player in meiotic recombination, a process essential for genetic diversity and genome stability. Its role in DNA binding also suggests potential implications in gene regulation and chromatin remodeling. The Anti-PRDM9 Antibody allows for the detection and analysis of PRDM9 expression in different cell types, making it a valuable tool for researchers studying genetics, reproductive biology, and developmental biology.
The importance of PRDM9 in meiotic recombination and DNA binding makes it a promising target for research into genetic disorders, infertility, and other related conditions. By understanding the function and regulation of PRDM9, researchers can uncover new insights into the mechanisms underlying these disorders and potentially develop novel therapeutic approaches.
Product Name:
Prdm9 Rabbit Polyclonal Antibody
SKU:
CAB20428
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 87-370 of mouse Prdm9 (NP_659058.3).
Enables DNA binding activity; histone-lysine N-methyltransferase activity; and protein homodimerization activity. Involved in several processes, including gamete generation; histone lysine methylation; and meiosis I. Acts upstream of or within several processes, including histone methylation; positive regulation of meiotic nuclear division; and positive regulation of transcription by RNA polymerase II. Located in chromatin and nucleus. Is expressed in embryo and head. Orthologous to human PRDM9 (PR/SET domain 9).
Purification Method:
Affinity purification
Gene ID:
213389
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Immunofluorescence analysis of mouse testis using Prdm9 Rabbit pAb (CAB20428) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
