The PR3 Monoclonal Antibody (CAB19748) is a high-quality antibody developed for reliable detection and analysis of target proteins. This polyclonal antibody, produced in rabbits, exhibits high reactivity with human samples and is specifically validated for use in Western blot applications. By binding to the proteinase 3 molecule, the antibody enables precise detection and analysis in a variety of cell types, making it an essential component for studies in immunology and autoimmune diseases.
This antibody is validated for use in ELISA, IF-P applications and has demonstrated reactivity against Human samples.
Product Name:
PR3 Monoclonal Antibody
SKU:
CAB19748
Size:
20μL, 100μL
Reactivity:
Human
Clone Number:
ARC2275
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Enables enzyme binding activity; serine-type endopeptidase activity; and signaling receptor binding activity. Involved in several processes, including mature conventional dendritic cell differentiation; membrane protein ectodomain proteolysis; and neutrophil extravasation. Located in azurophil granule lumen; cytosol; and plasma membrane raft. Colocalizes with plasma membrane.
Purification Method
Affinity purification
Gene ID
5657
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Confocal imaging of paraffin-embedded Human spleen using Proteinase 3/PR3 Rabbit mAb (CAB19748, dilution 1:200) followed by a further incubation with Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007, dilution 1:500) (Red). DAPI was used for nuclear staining (Blue). Objective: 40x. Perform high pressure antigen retrieval with 0.01 M citrate buffer (pH 6.0) prior to IF staining.
