The SMG1 Monoclonal Antibody (CAB19253) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in mice, specifically recognizes human SMG1 and has been validated for use in Western blot applications. By binding to the SMG1 protein, researchers can accurately detect and analyze its expression levels in a variety of cell types.SMG1 is essential for maintaining the integrity of the cellular mRNA pool by degrading aberrant transcripts and plays a crucial role in mRNA quality control mechanisms.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse samples.
Product Name:
SMG1 Monoclonal Antibody
SKU:
CAB19253
Size:
20μL, 100μL
Reactivity:
Mouse
Clone Number:
ARC2417
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
This gene encodes a protein involved in nonsense-mediated mRNA decay (NMD) as part of the mRNA surveillance complex. The protein has kinase activity and is thought to function in NMD by phosphorylating the regulator of nonsense transcripts 1 protein. Alternatively spliced transcript variants have been described, but their full-length nature has yet to be determined.
Purification Method
Affinity purification
Gene ID
23049
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using SMG1 Rabbit mAb (CAB19253) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
