The Tet3 Polyclonal Antibody (CAB20366) is specially designed for research involving Tet3, an enzyme that plays a crucial role in DNA demethylation and gene regulation. This antibody, produced in rabbits, is highly reactive with human samples and is validated for use in a variety of applications, including Western blotting. By binding to the Tet3 protein, this antibody allows for the detection and analysis of Tet3 expression in different cell types, making it an excellent tool for studies in epigenetics, stem cell biology, and developmental biology.Tet3 is known for its involvement in DNA demethylation processes, which are essential for regulating gene expression and maintaining cell identity.
Its role in epigenetic modifications makes it a key player in various biological processes, including embryonic development, cell differentiation, and disease progression. Research on Tet3 is therefore crucial for understanding epigenetic mechanisms and their impact on health and disease.Overall, the Tet3 Polyclonal Antibody (CAB20366) provides researchers with a valuable tool for studying Tet3 expression and function in different biological contexts. Its high specificity and sensitivity make it an indispensable resource for advancing our knowledge of epigenetics and its implications for various physiological and pathological processes.
Product Name:
TET3 Rabbit Polyclonal Antibody
SKU:
CAB20366
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1294-1553 of mouse TET3 (NP_898961.2).
cytoplasm, female pronucleus, male pronucleus, nucleoplasm, nucleus
Calculated MW:
195kDa
Observed MW:
230kDa
Enables methylcytosine dioxygenase activity. Involved in DNA demethylation of male pronucleus. Acts upstream of or within DNA demethylation. Located in cytoplasm; female pronucleus; and male pronucleus. Is expressed in several structures, including central nervous system; early conceptus; future brain; and genitourinary system. Orthologous to human TET3 (tet methylcytosine dioxygenase 3).
Purification Method:
Affinity purification
Gene ID:
194388
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of Neuro-2a cells, using TET3 antibody (CAB20366) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
